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Medchemexpress LLC (R)-1-Amino-18-(3,4-bis((4-fluorobenzyl)oxy)phenoxy)-3,6,9,12-tetraoxa-15-azaoctadecan-17-ol | 99.5% | 634.71 | 5 MG

Supplier: Medchemexpress LLC HY1693875MG
YT 6-2-PEG3-C2-NH2 is the p62/SQSTM1 targeting, autophagy-targeting ligand-linker conjugate of AUTOTAC ATC-324, which is an bivalent AR (Androgen Receptor) degrader. It can reduce nuclear AR levels and downregulate target gene expression of AR and AR-v7, and also has a degradation effect on common AR mutants in PCa.
- P62/SQSTM1 targeting
- Autophagy-targeting ligand-linker conjugate
- Reduces nuclear AR levels
- Downregulates target gene expression of AR and AR-v7
- Degradation effect on common AR mutants in PCa
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