(R)-1-Boc-3-hydroxypiperidine, 97%

Description

CAS: 143900-43-0 | C10H19NO3 | 201.266 g/mol

(R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. It has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. It has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.

Specifications

Chemical Identifiers

• CAS: 143900-43-0
• Molecular Formula: C10H19NO3
• Molecular Weight (g/mol): 201.266
• MDL Number: MFCD04115306
• InChI Key: UIJXHKXIOCDSEB-MRVPVSSYSA-N
• Synonym: r-1-boc-3-hydroxypiperidine, r-tert-butyl 3-hydroxypiperidine-1-carboxylate, tert-butyl 3r-3-hydroxypiperidine-1-carboxylate, r-1-n-boc-3-hydroxypiperidine, r-n-boc-3-hydroxypiperidine, r-1-boc-3-hydroxylpiperidine, 3r-1-tert-butoxycarbonyl-3-hydroxypiperidine, 1-piperidinecarboxylic acid, 3-hydroxy-, 1,1-dimethylethyl ester, 3r, r-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester, r-3-hydroxy-1-tert-butoxycarbonyl piperidine
• PubChem CID: 1514398
• IUPAC Name: tert-butyl (3R)-3-hydroxypiperidine-1-carboxylate
• SMILES: CC(C)(C)OC(=O)N1CCCC(C1)O

• Melting Point: 46°C to 50°C
• Flash Point: 104°C (219°F)
• Quantity: 1 g
• Optical Rotation: −23° (c=5 in Methanol)
• Formula Weight: 201.27
• Percent Purity: 97%
• Chemical Name or Material: (R)-1-Boc-3-hydroxypiperidine

Safety and Handling

Hazard Category	H301-H315-H318-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P362-P501c
DOTInformation	Hazard Class: 6.1; Packaging Group: III
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only