(R)-(+)-4-Hydroxy-2-pyrrolidinone, ≥97%, Thermo Scientific™

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
(R)-(+)-4-Hydroxy-2-pyrrolidinone intermediate in the preparation of Oxiracetam. Also used as enantiomeric intermediate for the asymmetric single isomeric drugs including antitumor, anesthetic, antipasmodic, anti-inflammatory or anti-HIV activity products.

Solubility
Slightly soluble in water.

Notes
Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Specifications

Chemical Identifiers

• CAS: 22677-21-0
• Molecular Formula: C4H7NO2
• Molecular Weight (g/mol): 101.11
• MDL Number: MFCD00273364
• InChI Key: IOGISYQVOGVIEU-GSVOUGTGSA-N
• Synonym: r-4-hydroxypyrrolidin-2-one, r-+-4-hydroxy-2-pyrrolidinone, r-4-hydroxy-2-pyrrolidone, 4r-4-hydroxypyrrolidin-2-one, r-4-hydroxy-2-pyrrolidinone, 4r-4-hydroxy-2-pyrrolidinone, r-4-hydroxy-pyrrolidin-2-one, 2-pyrrolidinone, 4-hydroxy-, 4r, r-+-4-hydroxy-2-pyrrolidone, rhpd
• PubChem CID: 185505
• IUPAC Name: (4R)-4-hydroxypyrrolidin-2-one
• SMILES: O[C@H]1CNC(=O)C1

• Melting Point: 155°C to 160°C
• Color: White to Yellow
• Quantity: 250 mg
• Beilstein: 1524193
• Solubility Information: Slightly soluble in water.
• Formula Weight: 101.1
• Percent Purity: ≥97%
• Physical Form: Powder
• Chemical Name or Material: (R)-(+)-4-Hydroxy-2-pyrrolidinone

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Ambient temperatures

SDS