(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99%

Description

CAS: 20445-31-2 | C10H9F3O3 | 234.17 g/mol

(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid is widely used reagent for determination of optical purities of alcohols and amines by 1H or 19F NMR.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid is widely used reagent for determination of optical purities of alcohols and amines by 1H or 19F NMR.

Solubility
Soluble in methanol (50 mg/ 1 ml).

Notes
Hygroscopic. Store under inert gas. Store away from oxidizing agents, moisture.

Specifications

Chemical Identifiers

• CAS: 20445-31-2
• Molecular Formula: C10H9F3O3
• Molecular Weight (g/mol): 234.17
• MDL Number: MFCD00004184
• InChI Key: JJYKJUXBWFATTE-UHFFFAOYNA-N
• PubChem CID: 2723917
• SMILES: COC(C(O)=O)(C1=CC=CC=C1)C(F)(F)F

• Melting Point: 43°C to 45°C
• Density: 1.344
• Boiling Point: 105°C to 107°C (1 mmHg)
• Flash Point: >110°C (230°F)
• Refractive Index: 1.473
• Quantity: 500 mg
• Beilstein: 2215440
• Sensitivity: Hygroscopic
• Merck Index: 14,6280
• Synonym: +-mtpa, unii-27o5l9t1wm, r-moshers acid, +-mosher's acid, 2r-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid, r-+-alpha-methoxy-alpha-trifluoromethylphenylacetic acid, r-mtpa, r-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid, r-+-a-methoxy-a-trifluoromethylphenylacetic acid, r-3,3,3-trifluoro-2-methoxy-2-phenyl-propionic acid
• Solubility Information: Soluble in methanol (50mg/ 1 ml).
• Optical Rotation: +72° (c=2 in Methanol)
• IUPAC Name: (2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid
• Formula Weight: 234.18
• Percent Purity: 99%
• Chemical Name or Material: (R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	243-829-5
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only