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Medchemexpress LLC (R)-Baclofen (Arbaclofen) | 69308-37-8 | 99.50% | 213.66 | 200 MG
Supplier: Medchemexpress LLC HY17354200MG
R-Baclofen (Arbaclofen) is a selective GABAB receptor agonist commonly used in research. It exhibits agonist activity at human GABA-B B1/B2 receptors expressed in HEK293 cells, as assessed by the inhibition of forskolin-stimulated cAMP accumulation. In vivo studies demonstrate its ability to suppress audiogenic seizures in Fmr1-knockout mice and significantly reduce seizure incidence with acute administration.
- Selective GABAB receptor agonist.
- Exhibits agonist activity at human GABA-B B1/B2 receptors.
- Suppresses audiogenic seizures in Fmr1-knockout mice.
- Reduces seizure incidence in mice.
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