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Medchemexpress LLC (R)-DRF053 dihydrochloride | 1241675-76-2 | >98.0% | 490.43 g/mol | C23H29Cl2N7O | 1 MG
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Supplier:  Medchemexpress LLC HY1033831MG

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(R)-DRF053 dihydrochloride is the dihydrochloride salt of a small-molecule inhibitor that targets casein kinase 1 and several cyclin-dependent kinases. It is supplied in small research quantities for use as a biochemical and cellular probe to study kinase signaling and amyloid-beta production.

  • Potent inhibition of CK1, CDK1/cyclin B, and CDK5/p25 with reported IC50s of 14 nM, 220 nM, and 80 nM respectively.
  • Dihydrochloride salt form suitable for biochemical and cellular assays.
  • High purity, typically >98% by HPLC.
  • Molecular weight approximately 490.43 g/mol and chemical formula C23H29Cl2N7O.
  • Available in small research quantities for preclinical use (for example, 1 mg packages).

Catalog No. 50-002-44806


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