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Medchemexpress LLC (R)-Ketorolac | 66635-93-6 | 99.7% | 100 MG
SDP

Catalog No. 5000409491
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(R)-Ketorolac is an orally active inhibitor of Cdc42 and Rac1. It functions by inhibiting GTPase activity and alters ovarian cancer cell behaviors critical for invasion and metastasis. (R)-Ketorolac also ameliorates cancer-associated cachexia.

  • Inhibits growth factor-dependent activation of Cdc42 and Rac1
  • Decreases the number and length of filopodia in SKOV3ip cells
  • Reduces adherence to fibronectin and collagen
  • Ameliorates cancer-associated cachexia in C26 tumor-bearing mice
  • Prolongs survival in C26 tumor-bearing mice
  • Effect is independent of tumor growth and food intake
  • Prevents C26-induced T-lymphopenia

Catalog No. 50-004-09491 Supplier Medchemexpress LLC Supplier No. HYB0580B100MG
May include imposed supplier surcharges.
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(R)-Ketorolac is an orally active inhibitor of Cdc42 and Rac1. It functions by inhibiting GTPase activity and alters ovarian cancer cell behaviors critical for invasion and metastasis. (R)-Ketorolac also ameliorates cancer-associated cachexia.

  • Inhibits growth factor-dependent activation of Cdc42 and Rac1
  • Decreases the number and length of filopodia in SKOV3ip cells
  • Reduces adherence to fibronectin and collagen
  • Ameliorates cancer-associated cachexia in C26 tumor-bearing mice
  • Prolongs survival in C26 tumor-bearing mice
  • Effect is independent of tumor growth and food intake
  • Prevents C26-induced T-lymphopenia

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