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Medchemexpress LLC (R)-Nimodipine | 77940-92-2 | 99.9% | 25 MG
Supplier: Medchemexpress LLC 25MGHYB0265A
(R)-Nimodipine is an orally active, blood-brain barrier-permeable L-type calcium channel blocker with an IC50 of 5 nM. It inhibits corticosterone release by blocking calcium channels on the hypothalamic-pituitary-adrenal axis, reversing immobilization stress-induced memory impairment and behavioral abnormalities. This compound is widely used in studies related to aneurysmal subarachnoid hemorrhage, cerebral ischemia, epilepsy, age-related degenerative neurological diseases, and alcohol intoxication.
- Orally active and blood-brain barrier-permeable
- L-type calcium channel blocker
- Inhibits corticosterone release
- Reverses immobilization stress-induced memory impairment
- Used in research for neurological and cerebrovascular diseases
- Inhibits slow inactivating Ca2+ currents in vitro
- Soluble in DMSO for experimental use
- Provided with in vivo protocols for various formulations
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