IgGs are glycoprotein antibodies that modulate several immune responses. IgG-Agarose is an immunoadsorbent that can be used to purify antibodies remove species specific cross-reacting antibodies or remove contaminating antibodies from an antiserum preparation. Characteristically cross-reacting antibodies may be removed from an antiserum preparation using an equal resin volume of IgG-Agarose. However the resin to antiserum ratio will vary with individual applications. Immunoglobulin G (IgG) is part of the immunoglobulin family and is a widely expressed serum antibody. It consists of a³ heavy chain in the constant (C) region. The monomeric 150kDa structure of IgG constitutes two identical heavy chains and two identical light chains with molecular weight of 50 kDa and 25 kDa respectively. The primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains linking the heavy and light chains and resides inside the chains. IgG is further subd