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Medchemexpress LLC (rac)-AR-13503 ((rac)-AR-13324 M1 metabolite) | 1254032-16-0 | 99.1% | 321.37 g/mol | C19H19N3O2 | 5MG
Supplier: Medchemexpress LLC HY1256395MG
(rac)-AR-13503 is a small-molecule ROCK/PKC inhibitor and an active metabolite of netarsudil. It inhibits angiogenesis, enhances retinal pigment epithelium (RPE) barrier function, and reduces aberrant neovascularization in preclinical models. The compound is provided as a high-purity research-grade solid for in vitro and in vivo studies.
- Inhibits ROCK and PKC signaling.
- Reduces angiogenesis and aberrant neovascularization in animal models.
- Enhances retinal pigment epithelium barrier function in dose-dependent assays.
- Active in vitro with HUVEC tube formation IC50 of approximately 21 nM.
- Provided as a high-purity research compound suitable for biological assays.
- Available in multiple small-mass package sizes for laboratory use.
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