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Medchemexpress LLC (Rac)-Modipafant (UK-74505) | 122956-68-7 | 98.2% | 605.09 | 25 MG
SDP

Catalog No. 5000347226
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(Rac)-Modipafant (UK-74505) is an orally active, selective, long-acting irreversible platelet activating factor receptor (PAFR) antagonist. It prevents dengue infection.

  • Prevents severe dengue infection at 10 mg/kg (p.o.; twice a day until day 10).
  • Exhibits highly selective, time-dependent inhibition of PAF-induced aggregation of rabbit washed platelets (IC50=26.3 and 1.12 nM after 0.25 and 60 min preincubation, respectively).
  • Dose-dependently inhibits zymosan-induced articular hyperalgesia at 5-20 mg/kg (p.o.).

Catalog No. 50-003-47226 Supplier Medchemexpress LLC Supplier No. 25MGHY108908
May include imposed supplier surcharges.
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(Rac)-Modipafant (UK-74505) is an orally active, selective, long-acting irreversible platelet activating factor receptor (PAFR) antagonist. It prevents dengue infection.

  • Prevents severe dengue infection at 10 mg/kg (p.o.; twice a day until day 10).
  • Exhibits highly selective, time-dependent inhibition of PAF-induced aggregation of rabbit washed platelets (IC50=26.3 and 1.12 nM after 0.25 and 60 min preincubation, respectively).
  • Dose-dependently inhibits zymosan-induced articular hyperalgesia at 5-20 mg/kg (p.o.).

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