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Medchemexpress LLC (Rac)-ZLc-002 | 99.0% | 231.25 | 100 MG
Supplier: Medchemexpress LLC HY124996100MG
(Rac)-ZLc-002 is an inhibitor of nNOS interaction with nitric oxide synthase 1 adaptor protein (NOS1AP). It suppresses inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with Paclitaxel to reduce tumor cell viability.
- Inhibitor of nNOS/NOS1AP interaction.
- Suppresses inflammatory nociception and chemotherapy-induced neuropathic pain.
- Synergizes with Paclitaxel to reduce tumor cell viability.
- Reduces co-immunoprecipitation of NOS1AP with nNOS in primary cultured cortical neurons.
- Attenuates mechanical and cold allodynia evoked by Paclitaxel in a mouse model.
- Reduces formalin-evoked nociceptive behavior in rats.
- Attenuates chronic mild stress (CMS)‐induced anxiogenic behavior in ICR mice.
- Reverses behavioral effects of glucocorticoids in mice.
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