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Medchemexpress LLC (Rac)-ZLc-002 | 99.0% | 231.25 | 50 MG
Supplier: Medchemexpress LLC HY12499650MG
(Rac)-ZLc-002 is an inhibitor of nNOS interaction with nitric oxide synthase 1 adaptor protein (NOS1AP). It suppresses inflammatory nociception and chemotherapy-induced neuropathic pain. Additionally, it synergizes with Paclitaxel to reduce tumor cell viability.
- Reduces co-immunoprecipitation of NOS1AP with nNOS immunoprecipitated from primary cultured cortical neurons
- Synergizes to reduce tumor cell viability
- Attenuates mechanical and cold allodynia evoked by Paclitaxel
- Reduces formalin-evoked nociceptive behavior and Fos-like immunoreactivity in the spinal dorsal horn
- Attenuates chronic mild stress (CMS)‐induced anxiogenic behavior
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