Apexbio Technology LLC Radezolid 869884-78-6 10mM (in 1mL DMSO)

Supplier:  Apexbio Technology LLC A37495.1

Radezolid is an oxazolidinone-class antibiotic under investigation targeting Gram-positive bacterial pathogens including methicillin-resistant Staphylococcus aureus (MRSA) By accumulating intracellularly within various host cells such as macrophages epithelial cells and endothelial cells Radezolid disrupts bacterial protein synthesis through inhibition of bacterial ribosomal translation In vitro assessments show antibacterial potency approximately tenfold greater than Linezolid at identical concentrations in infected cell models MIC90 values for MRSA strains indicate enhanced potency relative to Linezolid with MIC90 at approximately 0 5 mg/l compared to 2 0 mg/l for Linezolid Experimental animal models display increased Radezolid accumulation in infected tissues (2 4-fold higher tissue AUC compared to non-infected counterparts) Radezolid is explored in research settings examining complicated skin infections and community-acquired pneumonia (CAP)

Catalog No. 50-000-63975