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Medchemexpress LLC HY-123960A 5mg Medchemexpress, Raphin1 (acetate) CAS:2242616-04-0 Purity:>98%
Supplier: Medchemexpress LLC HY123960A5MG
Medchemexpress, HY-123960A 5mg Raphin1 (acetate) CAS:2242616-04-0 Raphin1 acetate is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B). Raphin1 acetate binds strongly to the R15B-PP1c holophosphatase (Kd=33 nM), and shows ~30-fold selective in binding R15B-PP1c over R15A-PP1c. Raphin1 acetate crosses the blood-brain barrier, and reduces organismal and molecular deficits in a mouse model of a protein misfolding disease. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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