Invitrogen™ Rat IL-6 ELISA (For Lysates) Kit

Catalog No.	Quantity
ERA32RBX5	5 x 96 Tests
ERA32RB	96 Tests

Catalog No. ERA32RBX5 Supplier Invitrogen™ Supplier No. ERA32RBX5

Description

ELISA

Rat IL-6 quantitates rat IL-6 in cell lysate, tissue homogenate. The assay will exclusively recognize both natural and recombinant rat IL-6.

IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells. The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections. The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.

Specifications

• Accession Number: B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; ChIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; Hybridoma growth factor; Ifnb2; IFN-beta-2; IL6; Il-6; ILg6; ILN; Interferon beta-2; Interleukin; interleukin 6; interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; Interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6
• Assay Range: 30 to 10,000 pg/mL
• Assay Sensitivity: 15 pg/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Cell Lysates, Tissue Homogenates
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 24498
• Gene Symbol: Il6
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Cell Lysate 50 μL, Tissue Homogenate 50 μL
• Storage Requirements: 2°C to 8°C
• Target: IL-6
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov