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Medchemexpress LLC RBN-3143 | 2360853-16-1 | C22H28FN3O4S | 5 MG
Supplier: Medchemexpress LLC HY1502075MG
RBN-3143 is a potent and NAD+-competitive catalytic PARP14 inhibitor with an IC50 value of 4 nM. It inhibits PARP14-mediated ADP-ribosylation and stabilizes PARP14 in cell lines. It can be used in research of lung inflammation.
- Potent and NAD+-competitive catalytic PARP14 inhibitor
- Inhibits PARP14-mediated ADP-ribosylation
- Stabilizes PARP14 in cell lines
- Used in research of lung inflammation
- Improves steroid-resistant asthma mouse models
- Suppresses alarmins TSLP, IL-33, and IL-25 in mouse models of asthma
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