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Medchemexpress LLC RBN-3143 | 2360853-16-1 | C22H28FN3O4S | 50 MG
Supplier: Medchemexpress LLC HY15020750MG
RBN-3143 is a potent and NAD+-competitive catalytic PARP14 inhibitor with an IC50 value of 4 nM. It inhibits PARP14-mediated ADP-ribosylation and stabilizes PARP14 in cell lines. RBN-3143 can be used in research of lung inflammation and has been shown to improve steroid-resistant asthma mouse models.
- Potent and NAD+-competitive catalytic PARP14 inhibitor with an IC50 value of 4 nM
- Inhibits PARP14-mediated ADP-ribosylation
- Stabilizes PARP14 in cell lines
- Can be used in research of lung inflammation
- Improves steroid-resistant asthma mouse models
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