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AdipoGen Rebaudioside A
SDP

Supplier:  AdipoGen CDXR0090G005

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Chemical. CAS 58543-16-1. Formula C44H70O23. MW 967.01. Rebaudioside A is a glucosylated steviol glycoside studied and used as a non-glycemic sweetener. It is one of the predominant steviol glycosides isolated from S. rebaudiana leaves. Rebaudioside A is a alpha-glucosidase inhibitor with IC50=35µg/ml and can inhibit ATP-sensitive K-channels. In vitro rebaudioside A stimulated the insulin secretion from MIN6 cells in a dose- and glucose-dependent manner. It increases glucagon-like peptide 1 GLP-1 secretion in a 2-dimensional mouse intestine model. Rebaudioside A is metabolized by gut microbiota to steviol. Rebaudioside A shows antioxidant activity on reducing cellular reactive oxygen species. It is an activator of Nrf2 and is a potential candidate hepatoprotective agent.

Catalog No. 50-256-0111


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