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Cayman Chemical Rec 152615hydrochlorIde 10mg
SDP

Supplier:  Cayman Chemical 2767710 MG

Encompass_Preferred

An α1B-AR antagonist (Ki = 0.45 nM for the recombinant human receptor); selectively inhibits α1B-ARs over α1A-, α1D-, and α1L-ARs (Kis = 7.59, 10.23, and 49 nM, respectively); inhibits norepinephrine-induced contractions of isolated rabbit prostate and urethral strips (Kis = 100 and 316.2 nM, respectively), and reduces norepinephrine-induced contractions of chloroethylclonidine-precontracted isolated rabbit aortic rings (Ki = 50 nM); decreases diastolic blood pressure (ED25 = 183 UG/kg, i.v.) and increases intracavernous pressure in anesthetized dogs when administered intracavernously at 30-1,000 UG/kg

Catalog No. 50-294-0298


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