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R&D Systems™ Recombinant Cynomolgus 4-1BB/TNFRSF9 Fc Chimera Protein

Catalog No. 93244B100
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93-244-B100 Quantity: 100μg
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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its binding ability in a functional ELISA. When Recombinant Cynomolgus Monkey 4-1BB/TNFRSF9/CD137 Fc Chimera is immobilized at 0.05 μg/mL (100 μL/well), Recombinant Human 4-1BB Ligand/TNFSF9 (Catalog # 2295-4L ) binds with an ED50 of 0.25-1.25 ng/mL.

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Ships at ambient temperature

Specifications

Accession Number XP_005544945
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Gene ID (Entrez) 3604
Molecular Weight (g/mol) M.W. (Observed): 56-66 kDa, reducing conditions; M.W. (theoretical): 44 kDa
Name 4-1BB/TNFRSF9 Fc Chimera Recombinant Protein
Quantity 100 μg
Source Human embryonic kidney cell, HEK293-derived cynomolgus monkey 4-1 BB/TNFRSF9/CD137 protein Cynomolgus Monkey 4-1 BB/TNFRSF9 (Leu24-Gln186) (N-terminus) Accession # XP_005544945 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Regulatory Status RUO
Structural Form Disulfide-linked homodimer
Endotoxin Concentration <0.10 EU / 1 μg of the protein by the LAL method.
Common Name 4-1BB ligand receptor; 41BB; 4-1BB; CD137 antigen; CD137; CD137MGC2172; CDw137; FLJ43501; ILA; ILAhomolog of mouse 4-1BB; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; receptor protein 4-1BB; T cell antigen
Biological Activity 0.25 to 1.25ng/mL
Product Type Recombinant Protein
Conjugate Unconjugated
Species Cynomolgus Monkey
Recombinant Recombinant
Reconstitution Reconstitute at 500 μg/mL in PBS.
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein 4-1 BB/TNFRSF9/CD137
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