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R&D Systems™ Recombinant Cynomolgus B7-H6 Fc Chimera Protein

Catalog No. 8984B7050
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8984B7050 50 μg
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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its ability to induce IFN-gamma secretion by NK-92 human natural killer lymphoma cells. Brandt, C.S. et al. (2009) J. Exp. Med. 206:1495. The ED50 for this effect is 0.5-2.5 μg/mL.

Specifications

Accession Number XP_005578557
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Gene ID (Entrez) 374383
Molecular Weight (g/mol) M.W. (Observed): 70-81 kDa, reducing conditions; M.W. (theoretical): 53 kDa
Quantity 50 μg
Source Human embryonic kidney cell, HEK293-derived cynomolgus monkey B7-H6 protein Cynomolgus B7-H6 (Asp25-Ser262) (N-terminus) Accession # XP_005578557 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU / 1 μg of the protein by the LAL method.
Gene Alias B7 homolog 6, B7H6, B7-H6, DKFZp686I21167, DKFZp686O24166, NCR3LG1
Common Name B7-H6
Gene Symbol NCR3LG1
Biological Activity Measured by its ability to induce IFN-gamma secretion by NK-92 human natural killer lymphoma cells. Brandt, C.S. et al. (2009) J. Exp. Med. 206:1495. The ED50 for this effect is typically 0.5-2.5μg/mL.
Conjugate Unconjugated
Species Cynomolgus Monkey
Recombinant Recombinant
Reconstitution Reconstitute at 100 μg/mL in PBS.
Expression System Human embryonic kidney cell, HEK293-derived Cynomolgus B7-H6 (Asp25-Ser262) Accession # XP_005578557, N-terminus; IEGRMD; Human IgG1 (Pro100-Lys330), C-terminus
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein B7-H6
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