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R&DSystems™ Recombinant Cynomolgus Monkey IL-4R alpha Fc Protein, CF

Catalog No. 115324R050
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11-532-4R050 50 μg
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Fc Chimera

Measured by its ability to inhibit IL-4-dependent proliferation of TF-1 human erythroleukemic cells. Kitamura, T. et al. (1989) J. Cell Physiol. 140:323. The ED50 for this effect is 9.00-90.0 ng/mL.

Specifications

Accession Number XP_005591574.2
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Gene ID (Entrez) 3566
Molecular Weight (g/mol) M.W.-observed: 70-79 kDa, under reducing conditions., M.W.-theroretical: 50 kDa
Quantity 50 μg
Source Human embryonic kidney cell, HEK293-derived cynomolgus monkey IL-4R alpha protein Cynomolgus Monkey IL-4R alpha (Met26-Arg232) (N-terminus) Accession # XP_005591574.2 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU per 1 μg of the protein by the LAL method.
Gene Alias CD124, CD124 antigen, IL-4 R alpha, IL-4 receptor subunit alpha, IL4R, IL4R alpha, IL-4R subunit alpha, IL-4RA, IL4RACD124, IL-4R-alpha, interleukin 4 receptor, interleukin-4 receptor alpha chain, interleukin-4 receptor subunit alpha
Conjugate Unconjugated
Reconstitution Reconstitute at 500 μg/mL in PBS.
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein IL-4R alpha
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