R&D Systems™ Recombinant Cynomolgus Monkey PD-L1/B7-H1 Fc Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. The ED50 for this effect is 2-10 μg/mL.

Order Info

Ships at ambient temperature.

Specifications

• Accession Number: XP_005581836
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 29126
• Molecular Weight (g/mol): M.W. (Observed): 58-75 kDa, reducing conditions; M.W. (theoretical): 52 kDa
• Quantity: 100 μg
• Source: Human embryonic kidney cell, HEK293-derived cynomolgus monkey PD-L1/B7-H1 protein Cynomolgus Monkey PD-L1 (Phe19-Thr239) (N-terminus) Accession # XP_005581836 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Regulatory Status: RUO
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Biological Activity: 2 to 10μg/mL
• Product Type: Recombinant protein
• Conjugate: Unconjugated
• Species: Cynomolgus Monkey
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 200 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: PD-L1

For Research Use Only.