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Apexbio Technology LLC Recombinant Human BMP-7 500ug
SDP

Supplier:  Apexbio Technology LLC P11570.5

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Bone Morphogenetic Protein 7 (BMP-7) also known as Osteogenic Protein-1 (OP-1) is a member of the TGF- superfamily It mediates biological effects by binding specific receptor complexes activating SMAD-dependent pathways to regulate osteoblast differentiation cartilage formation and kidney tissue development BMP-7 is predominantly expressed in kidney and bladder tissues and during embryonic development in the eye brain and ear Human BMP-7 is synthesized as a precursor with a 29-amino-acid signal peptide a 263-aa prodomain and a 139-aa mature domain showing strong conservation across species Recombinant Human BMP-7 (UniProt P18075 mature domain) expressed in E coli with a His-tag is commonly used in studies of osteogenic differentiation tissue regeneration and signal transduction both in vitro and in vivo

Catalog No. 50-000-63344


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