R&D Systems™ Recombinant Human CD46 Fc Chimera Protein

Catalog No.	Quantity
10-257-CD050	50 μg

Catalog No. 10-257-CD050 Supplier R&D Systems™ Supplier No. 10257CD050

Description

Measured by its binding ability in a functional ELISA.

When Recombinant Human CD46 Fc Chimera is immobilized at 5 μg/mL (100 μL/well), the concentration of Human C4b that produces 50% of the optimal binding response is 2 to 12 μg/mL.

Specifications

• Accession Number: P15529-11
• For Use With (Application): Bioactivity
• Gene ID (Entrez): 4179
• Molecular Weight (g/mol): 59 kDa
• Name: AHUS2, CD46, CD46 antigen, CD46 molecule, complement regulatory protein, MCP, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen
• Quantity: 50 μg
• Source:

  Chinese Hamster Ovary cell line, CHO-derived human CD46 protein

  Human CD46 (Cys35-Asp328) Accession # P15529-11IEGRMDHuman IgG1 (Pro100-Lys330)N-terminus C-terminus

• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Conjugate: Unconjugated
• Species: Human
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Endotoxin Level: <0.10 EU per 1 μg of the protein by the LAL method.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.