R&D Systems™ Recombinant Human FCRN Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

Non-covalently associated with endogenous beta 2-Microglobulin

Specifications

• Accession Number: P55899
• For Use With (Application): Bioactivity
• Gene ID (Entrez): 2217
• Molecular Weight (g/mol): Observed M.W.: 30-36kDa (FCRN), 10kDa ( beta 2 Microglobulin), Theoretical M.W.: 31kDa (FCRN), 10kDa ( beta 2 Microglobulin)kDa
• Quantity: 50 μg
• Source: Human embryonic kidney cell,HEK293-derived human FCRN protein Ala24-Ser297,with a C-terminal 6-His tag
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1μg of the protein by the LAL method.
• Gene Alias: alpha-chain, Fc fragment of IgG, receptor, transporter, alpha, FCGRT, FcRn, FcRn alpha chain, FCRNimmunoglobulin receptor, intestinal, heavy chain, IgG Fc fragment receptor transporter alpha chain, IgG receptor FcRn large subunit p51, major histocompatibility complex class I-like Fc receptor, Neonatal Fc receptor, neonatal Fc-receptor for Ig
• Common Name: FCRN/FCGRT
• Gene Symbol: FCGRT
• Biological Activity: Measured by its binding ability in a functional ELISA. When Recombinant Human FCRN is immobilized at 2μg/mL (100μL/well), the concentration of biotinylated human IgG that produces 50% of the optimal binding response is approximately 2-10μg/mL.
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Expression System: Human embryonic kidney cell, HEK293-derived Ala24-Ser297, with a C-terminal 6-His tag
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining