R&D Systems™ Recombinant Human IGF-I R/IGF1R Fc Chimera Protein, CF

Catalog No.
11-655-GR050	50 μg

Catalog No. 11-655-GR050 Supplier R&D Systems™ Supplier No. 11655GR050

Description

Recombinant Protein

Measured by its binding ability in a functional ELISA. Recombinant Human IGF-I R/IGF1R Fc Chimera (Catalog # 11655-GR binds to Recombinant Human IGF-I/IGF-1 (Catalog # 291-G1 ) with an ED50 of 3.00-45.0 ng/mL.

Specifications

• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 3480
• Molecular Weight (g/mol): MolecularWeight-observed: 160-180 kDa, 110-125 kDa and 70-80 kDa, under reducing conditions, MolecularWeight-theroretical: 130 kDa (single chain), 80 kDa (alpha subunit) and 49 kDa (beta subunit)
• Quantity: 50 μg
• Source: Human embryonic kidney cell, HEK293-derived human IGF-I R/IGF1R protein Human IGF1R (Glu31-His935) (N-terminus) Accession # P08069.1 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1 μg of the protein by the LAL method.
• Gene Alias: CD221, CD221 antigen, EC 2.7.10, EC 2.7.10.1, IGF1R, IGF-1R, IGF-I receptor, IGFIR, IGF-IR, IGFR, insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, JTK13, MGC142170, MGC142172, MGC18216, soluble IGF1R variant 1, soluble IGF1R variant 2
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 100 μg/mL in water.
• Protein: IGF-I R/IGF1R