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R&D Systems™ Recombinant Human IL-10 R alpha Fc Chimera Protein

Catalog No. 9044RI050
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90-44R-I050 50 μg
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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

The Recombinant Human IL-10 R alpha Fc Chimera Protein is derived from HEK293. The Recombinant Human IL-10 R alpha Fc Chimera Protein has been validated for the following applications: Bioactivity.

Specifications

Accession Number Q13651
For Use With (Application) Bioactivity
Gene ID (Entrez) 3587
Molecular Weight (g/mol) Observed M.W.: 64-78kDa, reducing conditions, Theoretical M.W.: 51kDa
Name IL-10R alpha
Quantity 50 μg
Source Human embryonic kidney cell,HEK293-derived human IL-10 R alpha protein, (N-terminus) Human IL-10 R alpha (His22-Asn235) Accession &Num; Q13651 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU per 1μg of the protein by the LAL method.
Gene Alias CD210 antigen, CDw210a, HIL-10R, IBD28, IL-10 receptor subunit alpha, IL10R alpha, IL-10R subunit 1, IL-10R1, IL10RA, IL-10RA, IL10RIL-10R subunit alpha, interleukin 10 receptor, alpha, interleukin-10 receptor alpha chain, Interleukin-10 receptor subunit 1, interleukin-10 receptor subunit alpha
Common Name IL-10 R alpha
Gene Symbol IL10RA
Biological Activity Measured by its ability to inhibit IL-10-dependent proliferation of MC/9-2 mouse mast cells. Thompson-Snipes, L. et al. (1991) J. Exp. Med. 173:507. The ED50 for this effect is typically 6-36ng/mL
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Expression System Human embryonic kidney cell, HEK293-derived Human IL-10 R alpha (His22-Asn235) Accession # Q13651, N-terminus; IEGRMD; Human IgG1 (Pro100-Lys330), C-terminus
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining
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