R&D Systems™ Recombinant Human Integrin alpha 2 beta 1 Protein

Description

Extensive quality control produces lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Binding Activity

Measured by its binding ability in a functional ELISA. When bovine collagen-II is coated at 10 μg/mL, Recombinant Human Integrin alpha 2 beta 1 binds with an apparent Kd <1nM.

Specifications

• Accession Number: NP_002194 (Integrin alpha 2) & P05556 (Integrin beta 1)
• For Use With (Application): Binding Activity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 3673
• Molecular Weight (g/mol): M.W. (Observed): 140-150 kDa (alpha 2) & 120-130 kDa (beta 1), reducing conditions; M.W. (theoretical): 126 kDa (alpha 2) & 83.3 kDa (beta 1)
• Name: Integrin alpha 2 beta 1
• Quantity: 50 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived human Integrin alpha 2 beta 1 protein Human Integrin alpha 2 (Tyr30-Thr1132) (N-terminus) Accession # NP_002194 HPGGGSGGGS Human c-Jun (Arg276-His315) Human Integrin beta 1 (Gln21-Asp728) (N-terminus) Accession # P05556 GGGSGGGS Human c-Fos (Leu161-Ala199) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Symbol: ITGA2
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 200 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: Integrin alpha 2 beta 1