R&D Systems™ Recombinant Human Integrin alpha V beta 3 Fc Protein, CF

Catalog No.
11-648-AV050	50 μg

Catalog No. 11-648-AV050 Supplier R&D Systems™ Supplier No. 11648AV050

Description

Fc Chimera

Measured by its binding ability in a functional ELISA. Recombinant Human Integrin alpha V beta 3 Fc Chimera (Catalog # 11648-AV) binds to Recombinant Human Vitronectin (Catalog # 2308-VN ) with an ED50 of 60.0-600 ng/mL.

Specifications

• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 3685
• Molecular Weight (g/mol): MolecularWeight-observed: >190 kDa, under non-reducing conditions., MolecularWeight-theroretical: 133 kDa (Integrin alpha V) & 103 kDa (Integrin beta 3)
• Quantity: 50 μg
• Source: Human embryonic kidney cell, HEK293-derived human Integrin alpha V beta 3 protein Human ITGAV (Phe31-Val992) (N-terminus) Accession # AAA36808.1 IEGR Human IgG1 (Glu99-Lys330) (with modifications) Human ITGB3 (Gly27-Asp718) (N-terminus) Accession # P05106.2 HPIEGR Human IgG1 (Glu99-Lys330) (with modifications) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1 μg of the protein by the LAL method.
• Gene Alias: antigen identified by monoclonal L230, CD51, CD51 antigen, integrin alpha-V, integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), MSK8, Vitronectin receptor subunit alpha, VNRADKFZp686A08142
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 250 μg/mL in water.
• Protein: Integrin alpha V beta 3