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R&D Systems™ Recombinant Human VSIG3 Fc Chimera Protein

Catalog No. 9229VS050
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92-29V-S050 Quantity: 50μg
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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

Measured by its ability to inhibit anti-CD3 antibody induced IL-17 secretion by human peripheral blood mononuclear cells (PBMC). The ED50 for this effect is 1-6 μg/mL.

Order Info

Ships at ambient temperature

Specifications

Accession Number BAC07546
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Gene ID (Entrez) 152404
Molecular Weight (g/mol) M.W. (Observed): 56-69 kDa, reducing conditions; M.W. (theoretical): 50 kDa
Name VSIG3 Fc Chimera Recombinant Protein
Quantity 50 μg
Source Mouse myeloma cell line, NS0-derived human VSIG3 protein Human VSIG3 (Leu23-Gly245) (N-terminus) Accession # BAC07546 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Regulatory Status RUO
Structural Form Disulfide-linked homodimer
Endotoxin Concentration <0.10 EU / 1 μg of the protein by the LAL method.
Common Name Brain and testis-specific immunoglobulin superfamily protein; BTIGSF; Bt-IGSF; cancer/testis antigen 119; CT119; CXADR like 1; CXADRL1; IGSF11; Igsf13; immunoglobulin superfamily member 11; immunoglobulin superfamily, member 11; MGC35227; V-set and immuno
Biological Activity 1 to 6μg/mL (ED 50)
Product Type Recombinant Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Reconstitution Reconstitute at 200 μg/mL in PBS.
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein VSIG3/IGSF11
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