R&D Systems™ Recombinant Mouse B7-H3 Fc Chimera Protein

Catalog No.	Quantity
10946B3050	50 μg

Catalog No. 10946B3050 Supplier R&D Systems™ Supplier No. 10946B3050

Description

Recombinant Protein

Measured by its ability to inhibit Mouse CD3 epsilon Antibody induced proliferation of Mouse T cells. The ED50 for this effect is 0.06-0.72 μg/mL.

Specifications

• Accession Number: Q8VE98.1
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 80381
• Molecular Weight (g/mol): MolecularWeight-observed: 65-73 kDa, under reducing conditions; MolecularWeight-theroretical: 50 kDa
• Quantity: 50 μg
• Source: Mouse myeloma cell line, NS0-derived mouse B7-H3 protein Mouse B7-H3 (Val29-Phe244) (N-terminus) Accession # Q8VE98.1 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: B7H3, B7H34Ig-B7-H3, B7-H3B7 homolog 3, CD276, CD276 antigen, CD276 molecule, Costimulatory molecule
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: B7-H3/CD276