R&D Systems™ Recombinant Mouse OX40/TNFRSF4 Fc Chimera Protein

Catalog No.	Quantity
1256OX050	50 μg

Catalog No. 1256OX050 Supplier R&D Systems™ Supplier No. 1256OX050

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

Measured by its ability to inhibit OX40 Ligand induced IL-2 secretion by mouse T cells. The ED50 for this effect is 0.1-0.3 μg/mL in the presence of 30 ng/mL of Recombinant Mouse OX40 Ligand/TNFSF4 (Catalog # 1236-OX ).

Specifications

• Accession Number: P47741
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 7293
• Molecular Weight (g/mol): M.W. (Observed): 65-75 kDa, reducing conditions; M.W. (theoretical): 48 kDa (monomer)
• Name: OX40/TNFRSF4 Fc Chimera
• Quantity: 50 μg
• Source: Mouse myeloma cell line, NS0-derived mouse OX40/TNFRSF4 protein Murine OX40 (Val20-Pro211) (N-terminus) Accession # P47741 DIEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Structural Form: Disulfide-linked homodimer
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Symbol: Tnfrsf4
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 100 μg/mL in sterile PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: OX40/TNFRSF4