R&D Systems™ Recombinant Mouse TrkB Fc Chimera Protein

Description

Measured by its ability to inhibit BDNF-induced proliferation of BaF-TrkB-BD mouse pro-B cells transfected with TrkB. The ED50 for this effect is 0.05 to 0.4 μg/mL.

Specifications

• Accession Number: P15209
• For Use With (Application): Bioactivity
• Gene ID (Entrez): 4915
• Molecular Weight (g/mol): 72 kDa
• Name: BDNF/NT-3 growth factors receptor, EC 2.7.10, EC 2.7.10.1, GP145-TrkB, Neurotrophic tyrosine kinase receptor type 2, neurotrophic tyrosine kinase, receptor, type 2, NTRK2, trk-B, TrkB tyrosine kinase, TRKBBDNF-tropomyosine receptor kinase B, tyrosine kinase receptor B
• Quantity: 50 μg
• Source:

  Mouse myeloma cell line, NS0-derived mouse TrkB protein

  Mouse TrkB (Cys32-His429) Accession # P15209IEGRMDPMouse IgG2a (Glu98-Lys330)N-terminus C-terminus

• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Conjugate: Unconjugated
• Species: Mouse
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Endotoxin Level: <0.10 EU per 1 μg of the protein by the LAL method.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.