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R&D Systems™ Recombinant Mouse TrkB Fc Chimera Protein

Catalog No. 10266TB050
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10-266-TB050 50 μg
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Measured by its ability to inhibit BDNF-induced proliferation of BaF-TrkB-BD mouse pro-B cells transfected with TrkB. The ED50 for this effect is 0.05 to 0.4 μg/mL.

Specifications

Accession Number P15209
For Use With (Application) Bioactivity
Gene ID (Entrez) 4915
Molecular Weight (g/mol) 72 kDa
Name BDNF/NT-3 growth factors receptor, EC 2.7.10, EC 2.7.10.1, GP145-TrkB, Neurotrophic tyrosine kinase receptor type 2, neurotrophic tyrosine kinase, receptor, type 2, NTRK2, trk-B, TrkB tyrosine kinase, TRKBBDNF-tropomyosine receptor kinase B, tyrosine kinase receptor B
Quantity 50 μg
Source

Mouse myeloma cell line, NS0-derived mouse TrkB protein

Mouse TrkB (Cys32-His429) Accession # P15209IEGRMDPMouse IgG2a (Glu98-Lys330)N-terminus C-terminus

Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Conjugate Unconjugated
Species Mouse
Reconstitution Reconstitute at 500 μg/mL in PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS.
Endotoxin Level <0.10 EU per 1 μg of the protein by the LAL method.
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
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