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ACROBiosystems RNF43 Protein, Human, Fc Tag, 100 μg

Catalog No. 502019434
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Human RNF43 protein acts as an E3 ubiquitin-protein ligase and serves as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis, and degradation of Frizzled receptor complex components. This protein, which also influences canonical and non-canonical signaling pathways, is expressed in human HEK293 cells. It is supplied as a lyophilized powder and includes a human IgG1 Fc tag at the C-terminus.

  • Greater than 95% purity as determined by SDS-PAGE
  • Calculated molecular weight of 43.5 kDa, migrating as 50-55 kDa under reducing conditions due to glycosylation
  • Endotoxin level less than 1.0 EU per μg
  • Expressed from human 293 cells
  • Verified by MALS analysis
  • Formulated in PBS, pH 7.4 with trehalose

Catalog No. 50-201-9434 Supplier ACROBiosystems Supplier No. RN3H5256100UG
May include imposed supplier surcharges.
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Human RNF43 protein acts as an E3 ubiquitin-protein ligase and serves as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis, and degradation of Frizzled receptor complex components. This protein, which also influences canonical and non-canonical signaling pathways, is expressed in human HEK293 cells. It is supplied as a lyophilized powder and includes a human IgG1 Fc tag at the C-terminus.

  • Greater than 95% purity as determined by SDS-PAGE
  • Calculated molecular weight of 43.5 kDa, migrating as 50-55 kDa under reducing conditions due to glycosylation
  • Endotoxin level less than 1.0 EU per μg
  • Expressed from human 293 cells
  • Verified by MALS analysis
  • Formulated in PBS, pH 7.4 with trehalose

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