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R&D Systems™ Recombinant Rat OX40/TNFRSF4 Fc Chimera Protein

Catalog No. 8584OX050
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85-84O-X050 50 μg
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Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its binding ability in a functional ELISA. When recombinant rat OX40 Ligand is coated at 75 ng/mL (100 μL/well), the concentration of Recombinant OX40 Fc Chimera that produces 50% optimal binding response is 1-5 ng/mL.

Specifications

Accession Number P15725
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Gene ID (Entrez) 7293
Molecular Weight (g/mol) M.W. (Observed): 67-78 kDa reducing conditions; M.W. (theoretical): 48 kDa (monomer)
Quantity 50 μg
Source Mouse myeloma cell line, NS0-derived rat OX40/TNFRSF4 protein Rat OX40/TNFRSF4 (Val20-Pro210) (N-terminus) Accession # P15725 IEGRMDP Mouse IgG2a (Glu98-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU / 1 μg of the protein by the LAL method.
Gene Alias ACT-135, ACT35 antigen, ACT35ATC35 antigen, CD134, CD134 antigen, Ly-70, OX40 cell surface antigen, OX40 homologue, OX40L receptor, OX40lymphoid activation antigene ACT35, TAX transcriptionally-activated glycoprotein 1 receptor, tax-transcriptionally activated glycoprotein 1 receptor, TNFRSF4, tumor necrosis factor receptor superfamily member 4, tumor necrosis factor receptor superfamily, member 4, Txgp1, TXGP1L, TXGP1LOX40 antigen
Common Name OX40/TNFRSF4
Gene Symbol Tnfrsf4
Biological Activity Measured by its binding ability in a functional ELISA. When recombinant rat OX40 Ligand is coated at 75ng/mL (100μL/well), the concentration of Recombinant OX40 Fc Chimera that produces 50% optimal binding response is typically 1-5ng/mL.
Conjugate Unconjugated
Species Rat
Recombinant Recombinant
Reconstitution Reconstitute at 100 μg/mL in PBS.
Expression System Mouse myeloma cell line, NS0-derived Rat OX40/TNFRSF4 (Val20-Pro210) Accession # P15725, N-terminus; IEGRMDP; Mouse IgG2a (Glu98-Lys330), C-terminus
Purity or Quality Grade >90%, by SDS-PAGE with silver staining
Protein OX40/TNFRSF4
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