R&D Systems™ Recombinant Rat TIM-3 Fc Chimera Protein

Catalog No.	Quantity
10489TM050	50 μg

Catalog No. 10489TM050 Supplier R&D Systems™ Supplier No. 10489TM050

Description

Carrier Free Recombinant Protein

Measured by its binding ability in a functional ELISA. When Recombinant Human Galectin-9 Protein (Catalog # 2045-GA ) is immobilized at 1.0 μg/mL (100 μL/ well), Recombinant Rat TIM-3 Fc Chimera (Catalog # 10489-TM) that produces a 50% optimal binding response is found to be 20-120 ng/mL

Specifications

• Accession Number: P0C0K5.2
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 84868
• Molecular Weight (g/mol): M.W.-observed: 60-75 kDa, under reducing conditions, M.W.-theoretical: 46 kDa
• Quantity: 50 μg
• Source: Mouse myeloma cell line, NS0-derived rat TIM-3 protein Rat TIM-3 (Leu22-Ala194) (N-terminus) Accession # P0C0K5.2 IEGRMD Mouse IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: CD366, FLJ14428, HAVcr-2, HAVCR2, hepatitis A virus cellular receptor 2, kidney injury molecule-3, KIM-3, SPTCL, T cell immunoglobulin mucin 3, T cell immunoglobulin mucin-3, T-cell immunoglobulin and mucin domain-containing protein 3, TIM 3, Tim-3, TIM3, TIM3 T-cell membrane protein 3, TIMD3, TIMD-3, TIMD3KIM-3
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 250 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: TIM-3