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Cayman Chemical Reduced HaloperIdol 10mg
Supplier: Cayman Chemical 2801710 MG
An active metabolite of haloperidol; formed via reduction of haloperidol by ketone reductase; inhibits radioligand binding to sigma-1 and dopamine D2 receptors (Kis = 1.4 and 31 nM, respectively); stimulates BDNF secretion from CCF-SSTG1 and U87MG astrocytic glial cells; inhibits norepinephrine, dopamine, and 5-HT reuptake (Kis = 21, 25, and 33 μM, respectively, in COS-7 cells expressing the human transporters); increases latency to paw withdrawal in mouse models of capsaicin-induced mechanical hypersensitivity at 0.5 mg/kg
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