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Apexbio Technology LLC Regadenoson 313348-27-5 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B59045.1
Regadenoson is a selective low-affinity agonist targeting the adenosine A2A receptor a G protein-coupled receptor involved in vasodilation mechanisms By activating A2A receptors regadenoson induces coronary vasodilation through increased coronary blood flow (CBF) Prior in vitro binding experiments show that regadenoson displays high specificity towards the A2A subtype without significant interaction with adenosine receptor subtypes A1 A2B or A3 In animal models intravenous regadenoson administration elevates coronary artery blood flow transiently in a dose-dependent manner with minimal systemic hemodynamic changes Clinically regadenoson induces rapid increases in human coronary blood flow velocity making it suitable for diagnostic research applications related to coronary function
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