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Medchemexpress LLC Rel-PROTAC PARP1 degrader | 99.0% | 1145.09 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY114324A

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rel-PROTAC PARP1 degrader is the relative configuration of ROTAC PARP1 degrader (HY-114324). ROTAC PARP1 degrader is a PARP1 degrader based on MDM2 E3 ligand. It induces significant PARP1 cleavage and programmed cell death. PROTAC PARP1 degrader at 10 μM at 24 h inhibits MDA-MB-231 cell line with an IC50 of 6.12 μM.

  • Relative configuration of ROTAC PARP1 degrader
  • Based on MDM2 E3 ligand
  • Induces significant PARP1 cleavage
  • Induces programmed cell death
  • Inhibits MDA-MB-231 cell line with an IC50 of 6.12 μM at 10 μM (24 h)
  • Purity: 98.99%
  • Molecular weight: 1145.09
  • Appearance: Solid
  • Color: White to off-white
  • Soluble in DMSO (110 mg/mL)

Catalog No. 50-004-38563


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