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Medchemexpress LLC Remodelin hydrobromide | 1622921-15-6 | 99.6% | 363.28 | 100 MG
Supplier: Medchemexpress LLC HY16706A100MG
Remodelin hydrobromide is an orally active and selective inhibitor of acetyltransferase NAT10. It inhibits NAT10 activity, slows DNA replication, and suppresses the growth of prostate cancer cells. It has been shown to inhibit the growth of prostate cancer and hepatocellular carcinoma in xenograft models. Additionally, Remodelin hydrobromide enhances the healthspan in the Hutchinson-Gilford progeria syndrome (HGPS) mouse model.
- Inhibits NAT10 activity and cell proliferation in prostate cancer cells.
- Slows DNA replication.
- Suppresses the growth of prostate cancer cells.
- Inhibits the growth of hepatocellular carcinoma in xenograft models.
- Enhances healthspan in the HGPS mouse model.
- Decreases nuclear shape defects and increases genomic stability in fibroblasts.
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