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Medchemexpress LLC Remodelin (hydrobromide) | 1622921-15-6 | 99.6% | 363.28 | 25 MG
Supplier: Medchemexpress LLC 25MGHY16706A
Remodelin hydrobromide is an orally active and selective inhibitor of acetyltransferase NAT10. It inhibits NAT10 activity, slows DNA replication, and suppresses the growth of prostate cancer cells. This compound has been shown to inhibit the growth of prostate cancer and hepatocellular carcinoma in xenograft models, and enhances healthspan in a Hutchinson-Gilford Progeria Syndrome (HGPS) mouse model.
- Orally active and selective NAT10 inhibitor
- Inhibits NAT10 activity and slows DNA replication
- Suppresses growth of prostate cancer cells
- Inhibits growth of prostate cancer and hepatocellular carcinoma in xenograft models
- Enhances healthspan in HGPS mouse model
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