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TARGETMOL CHEMICALS INC RESIQUIMOD 50MG
SDP

Supplier:  TARGETMOL CHEMICALS INC T6964

Encompass_Preferred

Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and activating TLR7 and 8 mainly on dendritic cells macrophages and B-lymphocytes. This induces the nuclear translocation of the transcription activator NF-kB as well as activation of other transcription factors. This may lead to an increase in mRNA levels and subsequent production of cytokines especially interferon-alpha (INF-a) and other cytokines thereby enhancing T-helper 1 (Th1) immune responses. In addition topical application of resiquimod appears to activate Langerhans' cells leading to an enhanced activation of T-lymphocytes. purity: 99%

Catalog No. 50-257-6402


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