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Cayman Chemical ResolvIn D2 AChE Tracer 100dtn

Supplier: Cayman Chemical 401120100 DTN

A glucocorticoid receptor agonist and an active metabolite of beclomethasone dipropionate binds to the glucocorticoid receptor (IC50 3 nM) inhibits PMA-induced glucocorticoid receptor transrepression as well as induces transactivation of the glucocorticoid receptor in CV-1 cells expressing the human receptor inhibits LPS-induced increases in IL-6 IL-8 and TNF-a levels in primary human lung macrophages from patients with COPD (IC50s 0.36 2.04 and 0.21 nM respectively)
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