Invitrogen™ Human RET [V804E], GST Tag Recombinant Protein

Description

Recombinant Protein

RET receptor tyrosine kinase or ret proto-oncogene is a member of the cadherin superfamily which are cell-surface molecules that transduce signals for cell growth and differentiation. RET can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. RET signaling pathway, by regulating the development of both the nervous and lymphoid system in the gut, plays a key role in the molecular mechanisms that orchestrate intestine organogenesis.

Specifications

• Accession Number: P07949
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50 mM HEPES with 100 mM NaCl, 15 mM glutathione, 20% glycerol, 5 mM DTT and no preservative; pH 7.5
• Gene ID (Entrez): 5979
• Molecular Weight (g/mol): 80.5 kDa
• Name: Human RET [V804E], GST Tag
• Quantity: 10 μg
• Gene Alias: RET
• Common Name: RET (V804E Mutant)
• KinaseFamily: RET Kinase Family
• Protein Length: 858-1114
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Shipping Condition: Dry Ice
• Expression System: Insect cells
• Protein Form: Recombinant, Active, Cytoplasmic, Mutant
• Form: Liquid