Retinoic acid, 97%

Description

All-trans-retinol, Vitamin A, retinol is a fat-soluble vitamin that binds retinoid receptors within cells. | CAS: 302-79-4 | C20H28O2 | 300.44 g/mol

Retinoic acid is used in dermatology drugs. It is used in the treatment of psoriasis, ichthyosis, follicular keratosis, acne, lichen planus, verrucous epidermal nevus and lichen psoriasis. It is also employed in promoting the proliferation and differentiation of epithelial cells. In addition to this, it exhibits some preventive effect on skin cancer.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• All-trans-retinol, commonly known as Vitamin A, is a fat-soluble essential nutrient

• All-trans-retinol is involved in hormonal signaling via the retinoid receptors

• It is an important regulator of cell division and apoptosis

• Deficiency can lead to vision, bone, immune, and skin disorders

Applications

• Suitable for research on cell differentiation, embryonic development, immunology and more

• Laboratory grade quality, for research use only

Specifications

Chemical Identifiers

• CAS: 302-79-4
• Molecular Formula: C20H28O2
• Molecular Weight (g/mol): 300.44
• MDL Number: MFCD00001551
• InChI Key: SHGAZHPCJJPHSC-YCNIQYBTSA-N
• Synonym: retinoic acid, tretinoin, vitamin a acid, all-trans-retinoic acid, trans-retinoic acid, renova, airol, retin-a, vesanoid, atra
• PubChem CID: 444795
• ChEBI: CHEBI:15367
• SMILES: C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O

• Melting Point: 180°C to 182°C
• Quantity: 0.1 g
• Beilstein: 2057223
• Sensitivity: Light sensitive
• Merck Index: 14,8165
• Solubility Information: Soluble in ethanol,acetate,dimethyl formamide,dimethyl sulfoxide,chloroform,methanol,acetone and dichloromethane. Insoluble in water and ether.
• IUPAC Name: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
• Formula Weight: 300.44
• Percent Purity: 98%
• Physical Form: Crystalline
• Chemical Name or Material: Retinoic acid

Safety and Handling

Hazard Category	H302+H312-H315-H319-H335-H361
Hazard Statement	GHS H Statement H361-H302 Suspected of damaging fertility or the unborn child. Harmful if swallowed.
Precautionary Statement	P201-P202-P261-P264b-P270-P271-P280-P281-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P312-P330-P332+P313-P362-P501c
EINECSNumber	206-129-0
RTECSNumber	VH6475000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only