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Medchemexpress LLC Revumenib | 2169919-21-3 | 99.99% | 630.82 | 200 MG
SDP

Supplier:  Medchemexpress LLC HY136175200MG

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Revumenib (SNDX-5613) is a potent and specific Menin-MLL inhibitor with a binding Ki of 0.149 nM and a cell-based IC50 of 10-20 nM. It is intended for the research of MLL-rearranged (MLL-r) acute leukemias, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). For research use only; not for sale to patients.

  • Potent and specific Menin-MLL inhibitor.
  • Applicable for research in MLL-rearranged acute leukemias (ALL and AML).
  • Shows in vivo plasma IC50 of 53 nM.
  • Provides significant survival benefit and leukemic control in aggressive MOLM-13 disseminated xenografts in vivo.

Catalog No. 50-003-49992


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