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Medchemexpress LLC Revumenib | 2169919-21-3 | 99.99% | 630.82 | 50 MG
Supplier: Medchemexpress LLC HY13617550MG
Revumenib (SNDX-5613) is a potent and specific Menin-MLL inhibitor with a binding Ki of 0.149 nM and a cell-based IC50 of 10-20 nM. It can be used for the research of MLL-rearranged (MLL-r) acute leukemias, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML).
- Potent and specific Menin-MLL inhibitor
- Applicable for research into MLL-rearranged acute leukemias (ALL and AML)
- Shows in vivo plasma IC50 of 53 nM
- Provides significant survival benefit and leukemic control in aggressive MOLM-13 disseminated xenografts in vivo
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