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Revvity Health Sciences Inc Revvity Cas9-gRNA Mito Depletion Enzyme, Human, Pre-complexed, 657 Guide RNAs
Supplier: Revvity Health Sciences Inc NOVA803100
The NEXTFLEX™ Cas9-gRNA Mito Depletion Enzyme (Human) is a flexible CRISPR-Cas9 module for removing mitochondrial derived sequences from human NGS libraries. It integrates into existing ATAC-seq, DNA-seq, bulk RNA-seq, or single-cell workflows at the double-stranded DNA stage, reducing mitochondrial background and focusing reads on nuclear genes and regulatory elements.
- Supplied as a pre-complexed Cas9–guide RNA mixture.
- Contains 657 guide RNAs targeting 17 mtDNA-encoded genes and selected nuclear mitochondrial pseudogenes.
- One unit is defined as the amount required to deplete 1–10 ng of target double-stranded DNA library of at least 400 bp.
- Delivers efficient mitochondrial depletion across diverse human library types.
- Designed for broad compatibility without locking the user into a particular library preparation kit or sequencing platform.
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